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Glutathione exists in cells in two states: reduced (GSH) and oxidized (GSSG)

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Figure 2 Compartmentalization of glutathione biosynthesis is unique to plants (Noctor et al., Plant GlutamateCysteine Ligase: Structure, Function, and Regulation Glutamatecysteine ligase catalyzes the ATP-dependent formation of a peptide bond between glutamate and cysteine in the first reaction of glutathione synthesis